Describe a hydropathy plot for a hypothetical integral membrane protein with 3 transmembrane segments and containing 190 amino acids.Does DNA supercoiling always require energy? write your answer with detailed reason, including what’s properties, mechanism makes it possible.
Meanwhile, Topoisomerase 1 does not use ATP to introduce supercoils, so It is called ‘self independent enzyme’.
What’s properties, mechanism makes it possible? Explain details.

  
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